Read About How Our Technology Has Been Used
Our patented technology has been utilised by scientists for several years now. And part of being a scientist is publishing data. Take a look at some of the scientific papers published to date, which utilised Sphere Fluidics’ picodroplet and microfluidic technology.
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Scientific Papers Available for Download
Abalde-Cela et al. 2015. High-throughput detection of ethanol-producing cyanobacteria in a microdroplet platform. J. R. Soc. Interface 12: 2015.0216
Bakewell et al. 2015. Information processing tools for extracting the electrical properties of nanoparticles. AIP Conf. Proc. 1646: 17-24
Bakewell et al 2015a. Real-time dielectrophoretic signalling and image quantification methods for evaluating electrokinetic properties of nanoparticles. Electrophoresis. 36(13): 1443–1450
Bakewell et al. 2016. Exploring and Evaluating Micro-environment and Nanoparticle Dielectrophoretic-induced Interactions with Image Analysis Methods. Materials Today: Proceedings, 3(3): 867-874
Chokkalingam et al. 2013. Probing cellular heterogeneity in cytokine-secreting immune cells using droplet-based microfluidics. Lab Chip 13: 4740-4744
Craig 2018. Microfluidics driving innovation and streamlining single cell analysis. Drug Discovery World Summer 2018: 61-66.
Crawford et al. 2017. Image-based closed-loop feedback for highly mono-dispersed microdroplet production . Scientific Reports 7, Article number: 10545
Holmes et al. 2014. Separation of blood cells with differing deformability using deterministic lateral displacement. Interface Focus 4. 20140011
Kruger et al. 2014. Deformability-based red blood cell separation in deterministic lateral displacement devices—A simulation study. Biomicrofluidics 8: 054114
Liu et al. 2016. High-throughput screening of antibiotic-resistant bacteria in picodroplets. Lab on a Chip, 2016, DOI: 10.1039/C6LC00180G
Ma et al. 2012. Fabrication of Microgel Particles with Complex Shape via Selective Polymerization of Aqueous Two-Phase Systems. Small. 8(15): 2356-2360
Ma et al. 2013. Monodisperse collagen–gelatin beads as potential platforms for 3D cell culturing. J. Mater. Chem. B, 1: 5128-5136
Morf J. et al. 2017. Spatial RNA proximities reveal a bipartite nucelar transciptome and territories of differential density and transcription elongation rates. BioRxiv:
Parker, R. M. et al. 2015. Electrostatically directed self-assembly of ultrathin supramolecular polymer microcapsules. Advanced Functional Materials. 25(26): 4091-4100.
Salmon et al. 2016. Monitoring early-stage nanoparticle assembly in microdroplets by optical spectroscopy and SERS. Small. Doi:10.1002/smll.201503513
Sherwood et al. 2014. Spatial Distributions of Red Blood Cells Significantly Alter Local Haemodynamics. PLOS One 9(6): :e100473
Shim et al. 2013. Ultrarapid Generation of Femtoliter Microfluidic Droplets for Single-Molecule-Counting Immunoassays. ACS Nano 7(7): 5955-5964
Smith et al. 2013. Sensitive, High Throughput Detection of Proteins in Individual, Surfactant-Stabilized Picoliter Droplets Using Nanoelectrospray Ionization Mass Spectrometry. Analytical Chemistry. 85(8): 3812-3816
Sphere Fluidics 2018. Designing a CRISPR experiment. Gene Editing 101 (2018 Edition). An introduction to Gene Editing: 18-26.
Use of standards for digital biological information in the design, construction and description of a synthetic biological system – Guide. 2015. PAS 246:2015